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Human NCK-interacting protein SH3 domain (aa 1-722 )
AF3P21 Swiss Prot#
Q9NZQ3
AF3P21 Protein names
NCK-interacting protein with SH3 domain (54 kDa VacA-interacting protein) (54 kDa vimentin-interacting protein) (VIP54) (90 kDa SH3 protein interacting with Nck) (AF3p21) (Dia-interacting protein 1) (DIP-1) (Diaphanous protein-interacting protein) (SH3 adapter protein SPIN90) (WASP-interacting SH3-domain protein) (WISH) (Wiskott-Aldrich syndrome protein-interacting protein)
AF3P21 Gene names
NCKIPSD AF3P21 SPIN90
Organism
Homo sapiens (Human)
AF3P21 Entry name
SPN90_HUMAN
AF3P21 Codon optimized cDNA(gene) Clone
AF3P21 Cat #
RPY1777
Tag
AF3P21 contains A 6x histidine tag
AF3P21 Formulation
Liquid
AF3P21 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
AF3P21 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant AF3P21 Protein
AF3P21 Cat #
PY1777
AF3P21 Source
recombinant
AF3P21 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
AF3P21 Purity
>90%, as determined by SDS-PAGE under reducing conditions
AF3P21 Activity
N/A
Tag
AF3P21 Contains A 6x histidine tag
AF3P21 Formulation
Liquid
AF3P21 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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AF3P21 family
-
AF3P21 Subcellular locations
Nucleus.
AF3P21 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1). Induces microspike formation, in vivo (By similarity). In vitro, stimulates N-WASP-induced ARP2/3 complex activation in the absence of CDC42 (By similarity). May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion.
AF3P21 Sequence
DDBJ EMBL GenBank
AF3P21 3D structure
ModBase
AF3P21 interaction
STRING
AF3P21 Proteomic
PRIDE
AF3P21 Genome annotation
Ensembl GeneID KEGG UCSC
AF3P21 Organism specific
CTD MGI
AF3P21 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
AF3P21 Gene expression
Bgee ArrayExpress Genevestigator
AF3P21 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY