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Human Engulfment cell motility protein 2 (aa 1-720 )

CED12A Swiss Prot#

Q96JJ3

CED12A Protein names

Engulfment and cell motility protein 2 (Protein ced-12 homolog A) (hCed-12A)

CED12A Gene names

ELMO2 CED12A KIAA1834

Organism

Homo sapiens (Human)

CED12A Entry name

ELMO2_HUMAN

CED12A Codon optimized cDNA(gene) Clone

CED12A Cat #

RPY1770

Tag

CED12A contains A 6x histidine tag

CED12A Formulation

Liquid

CED12A Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CED12A Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CED12A Protein

CED12A Cat #

PY1770

CED12A Source

recombinant

CED12A Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CED12A Purity

>90%, as determined by SDS-PAGE under reducing conditions

CED12A Activity

N/A

Tag

CED12A Contains A 6x histidine tag

CED12A Formulation

Liquid

CED12A Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CED12A family

-

CED12A Subcellular locations

Cytoplasm.

CED12A FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Involved in cytoskeletal rearrangements required for phagocytosis of apoptotic cells and cell motility. Acts in assocation with DOCK1 and CRK. Was initially proposed to be required in complex with DOCK1 to activate Rac Rho small GTPases. May enhance the guanine nucleotide exchange factor (GEF) activity of DOCK1.

CED12A Sequence

DDBJ

EMBL

GenBank

CED12A 3D structure

ModBase

CED12A interaction

STRING

CED12A Proteomic

PRIDE

CED12A Genome annotation

Ensembl

GeneID

KEGG

UCSC

CED12A Organism specific

CTD

MGI

CED12A Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CED12A Gene expression

Bgee

ArrayExpress

Genevestigator

CED12A Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY