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Human Exostosin-2 (aa 1-718 )

EXT2 Swiss Prot#

Q93063

EXT2 Protein names

Exostosin-2 (EC 2.4.1.224) (EC 2.4.1.225) (Glucuronosyl-N-acetylglucosaminyl-proteoglycan/N-acetylglucosaminyl-proteoglycan 4-alpha-N-acetylglucosaminyltransferase) (Multiple exostoses protein 2) (Putative tumor suppressor protein EXT2)

EXT2 Gene names

EXT2

Organism

Homo sapiens (Human)

EXT2 Entry name

EXT2_HUMAN

EXT2 Codon optimized cDNA(gene) Clone

EXT2 Cat #

RPY1761

Tag

EXT2 contains A 6x histidine tag

EXT2 Formulation

Liquid

EXT2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

EXT2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant EXT2 Protein

EXT2 Cat #

PY1761

EXT2 Source

recombinant

EXT2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

EXT2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

EXT2 Activity

N/A

Tag

EXT2 Contains A 6x histidine tag

EXT2 Formulation

Liquid

EXT2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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EXT2 family

Glycosyltransferase 47 family

EXT2 Subcellular locations

Endoplasmic reticulum membrane; Single-pass type II membrane protein. Golgi apparatus membrane; Single-pass type II membrane protein.

EXT2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Glycosyltransferase required for the biosynthesis of heparan-sulfate. The EXT1/EXT2 complex possesses substantially higher glycosyltransferase activity than EXT1 or EXT2 alone. Appears to be a tumor suppressor.

EXT2 Sequence

DDBJ

EMBL

GenBank

EXT2 3D structure

ModBase

EXT2 interaction

STRING

EXT2 Proteomic

PRIDE

EXT2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

EXT2 Organism specific

CTD

MGI

EXT2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

EXT2 Gene expression

Bgee

ArrayExpress

Genevestigator

EXT2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY