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Rat Amiloride-sensitive sodium channel subunit alpha (aa 1-698 )

Renac Swiss Prot#

P37089

Renac Protein names

Amiloride-sensitive sodium channel subunit alpha (Alpha-NaCH) (Epithelial Na(+) channel subunit alpha) (Alpha-ENaC) (Nonvoltage-gated sodium channel 1 subunit alpha) (SCNEA)

Renac Gene names

Scnn1a Renac

Organism

Rattus norvegicus (Rat)

Renac Entry name

SCNNA_RAT

Renac Codon optimized cDNA(gene) Clone

Renac Cat #

RPY1710

Tag

Renac contains A 6x histidine tag

Renac Formulation

Liquid

Renac Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Renac Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Renac Protein

Renac Cat #

PY1710

Renac Source

recombinant

Renac Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Renac Purity

>90%, as determined by SDS-PAGE under reducing conditions

Renac Activity

N/A

Tag

Renac Contains A 6x histidine tag

Renac Formulation

Liquid

Renac Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Renac family

Amiloride-sensitive sodium channel (TC 1.A.6) family, SCNN1A subfamily

Renac Subcellular locations

Apical cell membrane; Multi-pass membrane protein.

Renac FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Sodium permeable non-voltage-sensitive ion channel inhibited by the diuretic amiloride. Mediates the electrodiffusion of the luminal sodium (and water, which follows osmotically) through the apical membrane of epithelial cells. Controls the reabsorption of sodium in kidney, colon, lung and sweat glands. Also plays a role in taste perception.

Renac Sequence

DDBJ

EMBL

GenBank

Renac 3D structure

ModBase

Renac interaction

STRING

Renac Proteomic

PRIDE

Renac Genome annotation

Ensembl

GeneID

KEGG

UCSC

Renac Organism specific

CTD

MGI

Renac Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Renac Gene expression

Bgee

ArrayExpress

Genevestigator

Renac Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY