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Mouse Stromal interaction molecule 1 (aa 1-685 )

Sim Swiss Prot#

P70302

Sim Protein names

Stromal interaction molecule 1

Sim Gene names

Stim1 Sim

Organism

Mus musculus (Mouse)

Sim Entry name

STIM1_MOUSE

Sim Codon optimized cDNA(gene) Clone

Sim Cat #

RPY1684

Tag

Sim contains A 6x histidine tag

Sim Formulation

Liquid

Sim Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Sim Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Sim Protein

Sim Cat #

PY1684

Sim Source

recombinant

Sim Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Sim Purity

>90%, as determined by SDS-PAGE under reducing conditions

Sim Activity

N/A

Tag

Sim Contains A 6x histidine tag

Sim Formulation

Liquid

Sim Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Sim family

-

Sim Subcellular locations

Cell membrane; Single-pass type I membrane protein. Endoplasmic reticulum membrane; Single-pass type I membrane protein. Cytoplasm > cytoskeleton.

Sim FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Plays a role in mediating Ca(2+) influx following depletion of intracellular Ca(2+) stores. Acts as Ca(2+) sensor in the endoplasmic reticulum via its EF-hand domain. Upon Ca(2+) depletion, translocates from the endoplasmic reticulum to the plasma membrane where it activates the Ca(2+) release-activated Ca(2+) (CRAC) channel subunit, TMEM142A/ORAI1 (By similarity).

Sim Sequence

DDBJ

EMBL

GenBank

Sim 3D structure

ModBase

Sim interaction

STRING

Sim Proteomic

PRIDE

Sim Genome annotation

Ensembl

GeneID

KEGG

UCSC

Sim Organism specific

CTD

MGI

Sim Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Sim Gene expression

Bgee

ArrayExpress

Genevestigator

Sim Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY