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Mouse Fermitin family homolog 1 (aa 1-677 )

Kind1 Swiss Prot#

P59113

Kind1 Protein names

Fermitin family homolog 1 (Kindlin-1) (Unc-112-related protein 1)

Kind1 Gene names

Fermt1 Kind1 Urp1

Organism

Mus musculus (Mouse)

Kind1 Entry name

FERM1_MOUSE

Kind1 Codon optimized cDNA(gene) Clone

Kind1 Cat #

RPY1666

Tag

Kind1 contains A 6x histidine tag

Kind1 Formulation

Liquid

Kind1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Kind1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Kind1 Protein

Kind1 Cat #

PY1666

Kind1 Source

recombinant

Kind1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Kind1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Kind1 Activity

N/A

Tag

Kind1 Contains A 6x histidine tag

Kind1 Formulation

Liquid

Kind1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Kind1 family

Kindlin family

Kind1 Subcellular locations

Cytoplasm > cytoskeleton. Cell junction > focal adhesion. Cell projection > ruffle membrane; Peripheral membrane protein; Cytoplasmic side.

Kind1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Involved in cell adhesion. Contributes to integrin activation. When co-expressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites (By similarity).

Kind1 Sequence

DDBJ

EMBL

GenBank

Kind1 3D structure

ModBase

Kind1 interaction

STRING

Kind1 Proteomic

PRIDE

Kind1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Kind1 Organism specific

CTD

MGI

Kind1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Kind1 Gene expression

Bgee

ArrayExpress

Genevestigator

Kind1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY