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Human Fermitin family homolog 1 (aa 1-677 )

C20orf42 Swiss Prot#

Q9BQL6

C20orf42 Protein names

Fermitin family homolog 1 (Kindlerin) (Kindlin syndrome protein) (Kindlin-1) (Unc-112-related protein 1)

C20orf42 Gene names

FERMT1 C20orf42 KIND1 URP1

Organism

Homo sapiens (Human)

C20orf42 Entry name

FERM1_HUMAN

C20orf42 Codon optimized cDNA(gene) Clone

C20orf42 Cat #

RPY1665

Tag

C20orf42 contains A 6x histidine tag

C20orf42 Formulation

Liquid

C20orf42 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

C20orf42 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant C20orf42 Protein

C20orf42 Cat #

PY1665

C20orf42 Source

recombinant

C20orf42 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

C20orf42 Purity

>90%, as determined by SDS-PAGE under reducing conditions

C20orf42 Activity

N/A

Tag

C20orf42 Contains A 6x histidine tag

C20orf42 Formulation

Liquid

C20orf42 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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C20orf42 family

Kindlin family

C20orf42 Subcellular locations

Cytoplasm > cytoskeleton. Cell junction > focal adhesion. Cell projection > ruffle membrane; Peripheral membrane protein; Cytoplasmic side.

C20orf42 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Involved in cell adhesion. Contributes to integrin activation. When co-expressed with talin, potentiates activation of ITGA2B. Required for normal keratinocyte proliferation. Required for normal polarization of basal keratinocytes in skin, and for normal cell shape. Required for normal adhesion of keratinocytes to fibronectin and laminin, and for normal keratinocyte migration to wound sites. May mediate TGF-beta 1 signaling in tumor progression.

C20orf42 Sequence

DDBJ

EMBL

GenBank

C20orf42 3D structure

ModBase

C20orf42 interaction

STRING

C20orf42 Proteomic

PRIDE

C20orf42 Genome annotation

Ensembl

GeneID

KEGG

UCSC

C20orf42 Organism specific

CTD

MGI

C20orf42 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

C20orf42 Gene expression

Bgee

ArrayExpress

Genevestigator

C20orf42 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY