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Human Leucine zipper putative tumor suppressor 2 (aa 1-669 )

LZTS2 Swiss Prot#

Q9BRK4

LZTS2 Protein names

Leucine zipper putative tumor suppressor 2 (hLZTS2) (Protein LAPSER1)

LZTS2 Gene names

LZTS2 KIAA1813 LAPSER1

Organism

Homo sapiens (Human)

LZTS2 Entry name

LZTS2_HUMAN

LZTS2 Codon optimized cDNA(gene) Clone

LZTS2 Cat #

RPY1648

Tag

LZTS2 contains A 6x histidine tag

LZTS2 Formulation

Liquid

LZTS2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

LZTS2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant LZTS2 Protein

LZTS2 Cat #

PY1648

LZTS2 Source

recombinant

LZTS2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

LZTS2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

LZTS2 Activity

N/A

Tag

LZTS2 Contains A 6x histidine tag

LZTS2 Formulation

Liquid

LZTS2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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LZTS2 family

LZTS2 family

LZTS2 Subcellular locations

Cytoplasm. Cytoplasm > cytoskeleton > centrosome.

LZTS2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. May negatively regulate axonal outgrowth by preventing the formation of microtubule bundles that are necessary for transport within the elongating axon. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin.

LZTS2 Sequence

DDBJ

EMBL

GenBank

LZTS2 3D structure

ModBase

LZTS2 interaction

STRING

LZTS2 Proteomic

PRIDE

LZTS2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

LZTS2 Organism specific

CTD

MGI

LZTS2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

LZTS2 Gene expression

Bgee

ArrayExpress

Genevestigator

LZTS2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY