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Mouse Nuclear pore complex protein Nup85 (aa 1-656 )

Pcnt1 Swiss Prot#

Q8R480

Pcnt1 Protein names

Nuclear pore complex protein Nup85 (85 kDa nucleoporin) (FROUNT) (Nucleoporin Nup85) (Pericentrin-1)

Pcnt1 Gene names

Nup85 Pcnt1

Organism

Mus musculus (Mouse)

Pcnt1 Entry name

NUP85_MOUSE

Pcnt1 Codon optimized cDNA(gene) Clone

Pcnt1 Cat #

RPY1615

Tag

Pcnt1 contains A 6x histidine tag

Pcnt1 Formulation

Liquid

Pcnt1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Pcnt1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Pcnt1 Protein

Pcnt1 Cat #

PY1615

Pcnt1 Source

recombinant

Pcnt1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Pcnt1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Pcnt1 Activity

N/A

Tag

Pcnt1 Contains A 6x histidine tag

Pcnt1 Formulation

Liquid

Pcnt1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Pcnt1 family

Nucleoporin Nup85 family

Pcnt1 Subcellular locations

Nucleus > nuclear pore complex. Chromosome > centromere > kinetochore. Cytoplasm > cytoskeleton > spindle pole. Cytoplasm. Nucleus membrane.

Pcnt1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2-activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol-3-kinase-Rac-lammellipodium protrusion cascade.

Pcnt1 Sequence

DDBJ

EMBL

GenBank

Pcnt1 3D structure

ModBase

Pcnt1 interaction

STRING

Pcnt1 Proteomic

PRIDE

Pcnt1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Pcnt1 Organism specific

CTD

MGI

Pcnt1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Pcnt1 Gene expression

Bgee

ArrayExpress

Genevestigator

Pcnt1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY