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Human Nuclear pore complex protein Nup85 (aa 1-656 )

NUP75 Swiss Prot#

Q9BW27

NUP75 Protein names

Nuclear pore complex protein Nup85 (85 kDa nucleoporin) (FROUNT) (Nucleoporin Nup75) (Nucleoporin Nup85) (Pericentrin-1)

NUP75 Gene names

NUP85 NUP75 PCNT1

Organism

Homo sapiens (Human)

NUP75 Entry name

NUP85_HUMAN

NUP75 Codon optimized cDNA(gene) Clone

NUP75 Cat #

RPY1614

Tag

NUP75 contains A 6x histidine tag

NUP75 Formulation

Liquid

NUP75 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

NUP75 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant NUP75 Protein

NUP75 Cat #

PY1614

NUP75 Source

recombinant

NUP75 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

NUP75 Purity

>90%, as determined by SDS-PAGE under reducing conditions

NUP75 Activity

N/A

Tag

NUP75 Contains A 6x histidine tag

NUP75 Formulation

Liquid

NUP75 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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NUP75 family

Nucleoporin Nup85 family

NUP75 Subcellular locations

Nucleus > nuclear pore complex. Chromosome > centromere > kinetochore. Cytoplasm > cytoskeleton > spindle. Cytoplasm. Nucleus membrane.

NUP75 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Essential component of the nuclear pore complex (NPC) that seems to be required for NPC assembly and maintenance. As part of the NPC Nup107-160 subcomplex plays a role in RNA export and in tethering NUP98/Nup98 and NUP153 to the nucleus. The Nup107-160 complex seems to be required for spindle assembly during mitosis. NUP85 is required for membrane clustering of CCL2-activated CCR2. Seems to be involved in CCR2-mediated chemotaxis of monocytes and may link activated CCR2 to the phosphatidyl-inositol-3-kinase-Rac-lammellipodium protrusion cascade.

NUP75 Sequence

DDBJ

EMBL

GenBank

NUP75 3D structure

ModBase

NUP75 interaction

STRING

NUP75 Proteomic

PRIDE

NUP75 Genome annotation

Ensembl

GeneID

KEGG

UCSC

NUP75 Organism specific

CTD

MGI

NUP75 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

NUP75 Gene expression

Bgee

ArrayExpress

Genevestigator

NUP75 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY