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Human Katanin p80 WD40-containing subunit B1 (aa 1-655 )

KATNB1 Swiss Prot#

Q9BVA0

KATNB1 Protein names

Katanin p80 WD40-containing subunit B1 (Katanin p80 subunit B1) (p80 katanin)

KATNB1 Gene names

KATNB1

Organism

Homo sapiens (Human)

KATNB1 Entry name

KTNB1_HUMAN

KATNB1 Codon optimized cDNA(gene) Clone

KATNB1 Cat #

RPY1612

Tag

KATNB1 contains A 6x histidine tag

KATNB1 Formulation

Liquid

KATNB1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

KATNB1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant KATNB1 Protein

KATNB1 Cat #

PY1612

KATNB1 Source

recombinant

KATNB1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

KATNB1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

KATNB1 Activity

N/A

Tag

KATNB1 Contains A 6x histidine tag

KATNB1 Formulation

Liquid

KATNB1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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KATNB1 family

WD repeat KATNB1 family

KATNB1 Subcellular locations

Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle pole. Cytoplasm > cytoskeleton.

KATNB1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Participates in a complex which severs microtubules in an ATP-dependent manner. May act to target the enzymatic subunit of this complex to sites of action such as the centrosome. Microtubule severing may promote rapid reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Microtubule release from the mitotic spindle poles may allow depolymerization of the microtubule end proximal to the spindle pole, leading to poleward microtubule flux and poleward motion of chromosome. Microtubule release within the cell body of neurons may be required for their transport into neuronal processes by microtubule-dependent motor proteins. This transport is required for axonal growth (By similarity).

KATNB1 Sequence

DDBJ

EMBL

GenBank

KATNB1 3D structure

ModBase

KATNB1 interaction

STRING

KATNB1 Proteomic

PRIDE

KATNB1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

KATNB1 Organism specific

CTD

MGI

KATNB1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

KATNB1 Gene expression

Bgee

ArrayExpress

Genevestigator

KATNB1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY