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Human FYVE RhoGEF PH domain-containing protein 2 (aa 1-655 )
ZFYVE4 Swiss Prot#
Q7Z6J4
ZFYVE4 Protein names
FYVE, RhoGEF and PH domain-containing protein 2 (Zinc finger FYVE domain-containing protein 4)
ZFYVE4 Gene names
FGD2 ZFYVE4
Organism
Homo sapiens (Human)
ZFYVE4 Entry name
FGD2_HUMAN
ZFYVE4 Codon optimized cDNA(gene) Clone
ZFYVE4 Cat #
RPY1611
Tag
ZFYVE4 contains A 6x histidine tag
ZFYVE4 Formulation
Liquid
ZFYVE4 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
ZFYVE4 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant ZFYVE4 Protein
ZFYVE4 Cat #
PY1611
ZFYVE4 Source
recombinant
ZFYVE4 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
ZFYVE4 Purity
>90%, as determined by SDS-PAGE under reducing conditions
ZFYVE4 Activity
N/A
Tag
ZFYVE4 Contains A 6x histidine tag
ZFYVE4 Formulation
Liquid
ZFYVE4 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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ZFYVE4 family
-
ZFYVE4 Subcellular locations
Cytoplasm > cytoskeleton. Cytoplasm. Nucleus. Early endosome. Early endosome membrane. Cell projection > ruffle membrane.
ZFYVE4 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Activates CDC42, a member of the Ras-like family of Rho- and Rac proteins, by exchanging bound GDP for free GTP. Activates JNK1 via CDC42 but not RAC1. Binds to phosphatidylinositol 4,5-bisphosphate, phosphatidylinositol 3,4,5-trisphosphate, phosphatidylinositol 5-monophosphate, phosphatidylinositol 4-monophosphate and phosphatidylinositol 3-monophosphate (By similarity).
ZFYVE4 Sequence
DDBJ EMBL GenBank
ZFYVE4 3D structure
ModBase
ZFYVE4 interaction
STRING
ZFYVE4 Proteomic
PRIDE
ZFYVE4 Genome annotation
Ensembl GeneID KEGG UCSC
ZFYVE4 Organism specific
CTD MGI
ZFYVE4 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
ZFYVE4 Gene expression
Bgee ArrayExpress Genevestigator
ZFYVE4 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY