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Rat RalA-binding protein 1 (aa 1-647 )

Ralbp1 Swiss Prot#

Q62796

Ralbp1 Protein names

RalA-binding protein 1 (RalBP1) (Cytocentrin) (Dinitrophenyl S-glutathione ATPase) (DNP-SG ATPase) (Ral-interacting protein 1)

Ralbp1 Gene names

Ralbp1

Organism

Rattus norvegicus (Rat)

Ralbp1 Entry name

RBP1_RAT

Ralbp1 Codon optimized cDNA(gene) Clone

Ralbp1 Cat #

RPY1597

Tag

Ralbp1 contains A 6x histidine tag

Ralbp1 Formulation

Liquid

Ralbp1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Ralbp1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Ralbp1 Protein

Ralbp1 Cat #

PY1597

Ralbp1 Source

recombinant

Ralbp1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Ralbp1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Ralbp1 Activity

N/A

Tag

Ralbp1 Contains A 6x histidine tag

Ralbp1 Formulation

Liquid

Ralbp1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Ralbp1 family

-

Ralbp1 Subcellular locations

Membrane; Peripheral membrane protein. Cytoplasm > cytosol. Cytoplasm > cytoskeleton > spindle pole.

Ralbp1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Can activate specifically hydrolysis of GTP bound to RAC1 and CDC42, but not RALA. Mediates ATP-dependent transport of S-(2,4-dinitrophenyl)-glutathione (DNP-SG) and doxorubicin (DOX) and is the major ATP-dependent transporter of glutathione conjugates of electrophiles (GS-E) and DOX in erythrocytes. Can catalyze transport of glutathione conjugates and xenobiotics, and may contribute to the multidrug resistance phenomenon. Serves as a scaffold protein that brings together proteins forming an endocytotic complex during interphase and also with CDK1 to switch off endocytosis, One of its substrates would be EPN1/Epsin (By similarity). Involved in the assembly and function of the mitotic apparatus.

Ralbp1 Sequence

DDBJ

EMBL

GenBank

Ralbp1 3D structure

ModBase

Ralbp1 interaction

STRING

Ralbp1 Proteomic

PRIDE

Ralbp1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Ralbp1 Organism specific

CTD

MGI

Ralbp1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Ralbp1 Gene expression

Bgee

ArrayExpress

Genevestigator

Ralbp1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY