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Human Influenza virus NS1A-binding protein (aa 1-642 )

ARA3 Swiss Prot#

Q9Y6Y0

ARA3 Protein names

Influenza virus NS1A-binding protein (NS1-BP) (NS1-binding protein) (Aryl hydrocarbon receptor-associated protein 3)

ARA3 Gene names

IVNS1ABP ARA3 FLARA3 KIAA0850 NS1 NS1BP HSPC068

Organism

Homo sapiens (Human)

ARA3 Entry name

NS1BP_HUMAN

ARA3 Codon optimized cDNA(gene) Clone

ARA3 Cat #

RPY1580

Tag

ARA3 contains A 6x histidine tag

ARA3 Formulation

Liquid

ARA3 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

ARA3 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant ARA3 Protein

ARA3 Cat #

PY1580

ARA3 Source

recombinant

ARA3 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

ARA3 Purity

>90%, as determined by SDS-PAGE under reducing conditions

ARA3 Activity

N/A

Tag

ARA3 Contains A 6x histidine tag

ARA3 Formulation

Liquid

ARA3 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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ARA3 family

-

ARA3 Subcellular locations

Cytoplasm. Cytoplasm > cytoskeleton. Nucleus > nucleoplasm.

ARA3 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Plays a role in cell division and in the dynamic organization of the actin skeleton as a stabilizer of actin filaments by association with F-actin through Kelch repeats. Protects cells from cell death induced by actin destabilization; Protects neurons from dendritic spines and actin filaments damage induced by the actin-destabilizing cytochalasin B when overexpressed. Activates Erk signaling pathway when overexpressed in cultured cell lines (By similarity). May be a component of the cellular splicing machinery with a role in pre-mRNA splicing; may mediate the inhibition of splicing by NS/influenza virus NS1A protein. Functions as modifier of the AHR/Aryl hydrocarbon receptor pathway increasing the concentration of AHR available to activate transcription.

ARA3 Sequence

DDBJ

EMBL

GenBank

ARA3 3D structure

ModBase

ARA3 interaction

STRING

ARA3 Proteomic

PRIDE

ARA3 Genome annotation

Ensembl

GeneID

KEGG

UCSC

ARA3 Organism specific

CTD

MGI

ARA3 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

ARA3 Gene expression

Bgee

ArrayExpress

Genevestigator

ARA3 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY