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Mouse Rho guanine nucleotide exchange factor 25 (aa 1-618 )

Arhgef25 Swiss Prot#

Q9CWR0

Arhgef25 Protein names

Rho guanine nucleotide exchange factor 25 (Guanine nucleotide exchange factor GEFT) (Rac/Cdc42/Rho exchange factor GEFT) (RhoA/Rac/Cdc42 guanine nucleotide exchange factor GEFT) (p63RhoGEF)

Arhgef25 Gene names

Arhgef25 D10Ertd610e Geft

Organism

Mus musculus (Mouse)

Arhgef25 Entry name

ARHGP_MOUSE

Arhgef25 Codon optimized cDNA(gene) Clone

Arhgef25 Cat #

RPY1532

Tag

Arhgef25 contains A 6x histidine tag

Arhgef25 Formulation

Liquid

Arhgef25 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Arhgef25 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Arhgef25 Protein

Arhgef25 Cat #

PY1532

Arhgef25 Source

recombinant

Arhgef25 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Arhgef25 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Arhgef25 Activity

N/A

Tag

Arhgef25 Contains A 6x histidine tag

Arhgef25 Formulation

Liquid

Arhgef25 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Arhgef25 family

-

Arhgef25 Subcellular locations

Cytoplasm > myofibril > sarcomere. Cell membrane. Cytoplasm > myofibril.

Arhgef25 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: May play a role in actin cytoskeleton reorganization in different tissues since its activation induces formation of actin stress fibers. It works as a guanine nucleotide exchange factor for Rho family of small GTPases. Links specifically G alpha q/11-coupled receptors to RHOA activation (By similarity). May be an important regulator of processes involved in axon and dendrite formation. In neurons seems to be an exchange factor primarily for RAC1. Involved in skeletal myogenesis.

Arhgef25 Sequence

DDBJ

EMBL

GenBank

Arhgef25 3D structure

ModBase

Arhgef25 interaction

STRING

Arhgef25 Proteomic

PRIDE

Arhgef25 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Arhgef25 Organism specific

CTD

MGI

Arhgef25 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Arhgef25 Gene expression

Bgee

ArrayExpress

Genevestigator

Arhgef25 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY