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Mouse Spastin (aa 1-614 )

Spast Swiss Prot#

Q9QYY8

Spast Protein names

Spastin (EC 3.6.4.3)

Spast Gene names

Spast Kiaa1083 Spg4

Organism

Mus musculus (Mouse)

Spast Entry name

SPAST_MOUSE

Spast Codon optimized cDNA(gene) Clone

Spast Cat #

RPY1523

Tag

Spast contains A 6x histidine tag

Spast Formulation

Liquid

Spast Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Spast Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Spast Protein

Spast Cat #

PY1523

Spast Source

recombinant

Spast Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Spast Purity

>90%, as determined by SDS-PAGE under reducing conditions

Spast Activity

N/A

Tag

Spast Contains A 6x histidine tag

Spast Formulation

Liquid

Spast Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Spast family

AAA ATPase family, Spastin subfamily

Spast Subcellular locations

Membrane; Single-pass membrane protein. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton. Cytoplasm > perinuclear region. Endoplasmic reticulum. Endosome. Nucleus. Cytoplasm > cytoskeleton > spindle.

Spast FUNCTION According to UniProtKB Swiss Prot

FUNCTION: ATP-dependent microtubule severing protein. Microtubule severing may promote reorganization of cellular microtubule arrays and the release of microtubules from the centrosome following nucleation. Required for membrane traffic from the endoplasmic reticulum (ER) to the Golgi and for completion of the abscission stage of cytokinesis (By similarity). Required for development of axonal processes and for axonal branching.

Spast Sequence

DDBJ

EMBL

GenBank

Spast 3D structure

ModBase

Spast interaction

STRING

Spast Proteomic

PRIDE

Spast Genome annotation

Ensembl

GeneID

KEGG

UCSC

Spast Organism specific

CTD

MGI

Spast Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Spast Gene expression

Bgee

ArrayExpress

Genevestigator

Spast Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY