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Mouse Protein Spindly (aa 1-608 )
Ccdc99 Swiss Prot#
Q923A2
Ccdc99 Protein names
Protein Spindly (Coiled-coil domain-containing protein 99)
Ccdc99 Gene names
Ccdc99
Organism
Mus musculus (Mouse)
Ccdc99 Entry name
SPDLY_MOUSE
Ccdc99 Codon optimized cDNA(gene) Clone
Ccdc99 Cat #
RPY1512
Tag
Ccdc99 contains A 6x histidine tag
Ccdc99 Formulation
Liquid
Ccdc99 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
Ccdc99 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant Ccdc99 Protein
Ccdc99 Cat #
PY1512
Ccdc99 Source
recombinant
Ccdc99 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
Ccdc99 Purity
>90%, as determined by SDS-PAGE under reducing conditions
Ccdc99 Activity
N/A
Tag
Ccdc99 Contains A 6x histidine tag
Ccdc99 Formulation
Liquid
Ccdc99 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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Ccdc99 family
Spindly family
Ccdc99 Subcellular locations
Cytoplasm > cytoskeleton > centrosome. Chromosome > centromere > kinetochore. Nucleus. Cytoplasm > cytoskeleton > spindle pole.
Ccdc99 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment (By similarity).
Ccdc99 Sequence
DDBJ EMBL GenBank
Ccdc99 3D structure
ModBase
Ccdc99 interaction
STRING
Ccdc99 Proteomic
PRIDE
Ccdc99 Genome annotation
Ensembl GeneID KEGG UCSC
Ccdc99 Organism specific
CTD MGI
Ccdc99 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
Ccdc99 Gene expression
Bgee ArrayExpress Genevestigator
Ccdc99 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY