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Rat Protein Spindly (aa 1-597 )

Ccdc99 Swiss Prot#

Q3KR99

Ccdc99 Protein names

Protein Spindly (Coiled-coil domain-containing protein 99)

Ccdc99 Gene names

Ccdc99

Organism

Rattus norvegicus (Rat)

Ccdc99 Entry name

SPDLY_RAT

Ccdc99 Codon optimized cDNA(gene) Clone

Ccdc99 Cat #

RPY1487

Tag

Ccdc99 contains A 6x histidine tag

Ccdc99 Formulation

Liquid

Ccdc99 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Ccdc99 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Ccdc99 Protein

Ccdc99 Cat #

PY1487

Ccdc99 Source

recombinant

Ccdc99 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Ccdc99 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Ccdc99 Activity

N/A

Tag

Ccdc99 Contains A 6x histidine tag

Ccdc99 Formulation

Liquid

Ccdc99 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Ccdc99 family

Spindly family

Ccdc99 Subcellular locations

Cytoplasm > cytoskeleton > centrosome. Chromosome > centromere > kinetochore. Nucleus. Cytoplasm > cytoskeleton > spindle pole.

Ccdc99 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Required for the localization of dynein and dynactin to the mitotic kintochore. Dynein is believed to control the initial lateral interaction between the kinetochore and spindle microtubules and to facilitate the subsequent formation of end-on kinetochore-microtubule attachments mediated by the NDC80 complex. Also required for correct spindle orientation. Does not appear to be required for the removal of spindle assembly checkpoint (SAC) proteins from the kinetochore upon bipolar spindle attachment (By similarity).

Ccdc99 Sequence

DDBJ

EMBL

GenBank

Ccdc99 3D structure

ModBase

Ccdc99 interaction

STRING

Ccdc99 Proteomic

PRIDE

Ccdc99 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Ccdc99 Organism specific

CTD

MGI

Ccdc99 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Ccdc99 Gene expression

Bgee

ArrayExpress

Genevestigator

Ccdc99 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY