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Rat Kelch-like protein 21 (aa 1-597 )

Klhl21 Swiss Prot#

D4A2K4

Klhl21 Protein names

Kelch-like protein 21

Klhl21 Gene names

Klhl21

Organism

Rattus norvegicus (Rat)

Klhl21 Entry name

KLH21_RAT

Klhl21 Codon optimized cDNA(gene) Clone

Klhl21 Cat #

RPY1486

Tag

Klhl21 contains A 6x histidine tag

Klhl21 Formulation

Liquid

Klhl21 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Klhl21 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Klhl21 Protein

Klhl21 Cat #

PY1486

Klhl21 Source

recombinant

Klhl21 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Klhl21 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Klhl21 Activity

N/A

Tag

Klhl21 Contains A 6x histidine tag

Klhl21 Formulation

Liquid

Klhl21 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Klhl21 family

-

Klhl21 Subcellular locations

Cytoplasm > cytoskeleton > spindle.

Klhl21 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Substrate-specific adapter of BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for efficient chromosome alignment and cytokinesis. The BCR(KLHL21) E3 ubiquitin ligase complex regulates localization of the chromosomal passenger complex (CPC) from chromosomes to the spindle midzone in anaphase and mediates the ubiquitination of AURKB. Ubiquitination of AURKB by BCR(KLHL21) E3 ubiquitin ligase complex may not lead to its degradation by the proteasome (By similarity).

Klhl21 Sequence

DDBJ

EMBL

GenBank

Klhl21 3D structure

ModBase

Klhl21 interaction

STRING

Klhl21 Proteomic

PRIDE

Klhl21 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Klhl21 Organism specific

CTD

MGI

Klhl21 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Klhl21 Gene expression

Bgee

ArrayExpress

Genevestigator

Klhl21 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY