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| Human Sorting nexin-9 (aa 1-595 ) |
| SH3PX1 Swiss Prot# | | Q9Y5X1 |
| SH3PX1 Protein names | | Sorting nexin-9 (SH3 and PX domain-containing protein 1) (Protein SDP1) (SH3 and PX domain-containing protein 3A) |
| SH3PX1 Gene names | | SNX9 SH3PX1 SH3PXD3A |
| Organism | | Homo sapiens (Human) |
| SH3PX1 Entry name | | SNX9_HUMAN |
| SH3PX1 Codon optimized cDNA(gene) Clone |
| SH3PX1 Cat # | | RPY1472 |
| Tag | | SH3PX1 contains A 6x histidine tag |
| SH3PX1 Formulation | | Liquid |
| SH3PX1 Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| SH3PX1 Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant SH3PX1 Protein |
| SH3PX1 Cat # | | PY1472 |
| SH3PX1 Source | | recombinant |
| SH3PX1 Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| SH3PX1 Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| SH3PX1 Activity | | N/A |
| Tag | | SH3PX1 Contains A 6x histidine tag |
| SH3PX1 Formulation | | Liquid |
| SH3PX1 Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant SH3PX1 Products | | For pricing and availability Click Here >>> |
| SH3PX1 family | | Sorting nexin family |
| SH3PX1 Subcellular locations | | Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle > clathrin-coated vesicle. Golgi apparatus > trans-Golgi network. Cell projection > ruffle. Cytoplasm. |
| SH3PX1 FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: May be involved in several stages of intracellular trafficking. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Promotes internalization of TNFR. Promotes degradation of EGFR after EGF signaling. Stimulates the GTPase activity of DNM1. Promotes DNM1 oligomerization. Promotes activation of the Arp2/3 complex by WASL, and thereby plays a role in the reorganization of the F-actin cytoskeleton. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Has lower affinity for membranes enriched in phosphatidylinositol 3-phosphate. |
| SH3PX1 Sequence | | DDBJ | EMBL | GenBank |
| SH3PX1 3D structure | | ModBase |
| SH3PX1 interaction | | STRING |
| SH3PX1 Proteomic | | PRIDE |
| SH3PX1 Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| SH3PX1 Organism specific | | CTD | MGI |
| SH3PX1 Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| SH3PX1 Gene expression | | Bgee | ArrayExpress | Genevestigator |
| SH3PX1 Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |