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Human Sorting nexin-9 (aa 1-595 )
SH3PX1 Swiss Prot#
Q9Y5X1
SH3PX1 Protein names
Sorting nexin-9 (SH3 and PX domain-containing protein 1) (Protein SDP1) (SH3 and PX domain-containing protein 3A)
SH3PX1 Gene names
SNX9 SH3PX1 SH3PXD3A
Organism
Homo sapiens (Human)
SH3PX1 Entry name
SNX9_HUMAN
SH3PX1 Codon optimized cDNA(gene) Clone
SH3PX1 Cat #
RPY1472
Tag
SH3PX1 contains A 6x histidine tag
SH3PX1 Formulation
Liquid
SH3PX1 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
SH3PX1 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant SH3PX1 Protein
SH3PX1 Cat #
PY1472
SH3PX1 Source
recombinant
SH3PX1 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
SH3PX1 Purity
>90%, as determined by SDS-PAGE under reducing conditions
SH3PX1 Activity
N/A
Tag
SH3PX1 Contains A 6x histidine tag
SH3PX1 Formulation
Liquid
SH3PX1 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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SH3PX1 family
Sorting nexin family
SH3PX1 Subcellular locations
Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle > clathrin-coated vesicle. Golgi apparatus > trans-Golgi network. Cell projection > ruffle. Cytoplasm.
SH3PX1 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: May be involved in several stages of intracellular trafficking. Plays a role in endocytosis via clathrin-coated pits, but also clathrin-independent, actin-dependent fluid-phase endocytosis. Plays a role in macropinocytosis. Promotes internalization of TNFR. Promotes degradation of EGFR after EGF signaling. Stimulates the GTPase activity of DNM1. Promotes DNM1 oligomerization. Promotes activation of the Arp2/3 complex by WASL, and thereby plays a role in the reorganization of the F-actin cytoskeleton. Binds to membranes enriched in phosphatidylinositol 4,5-bisphosphate and promotes membrane tubulation. Has lower affinity for membranes enriched in phosphatidylinositol 3-phosphate.
SH3PX1 Sequence
DDBJ EMBL GenBank
SH3PX1 3D structure
ModBase
SH3PX1 interaction
STRING
SH3PX1 Proteomic
PRIDE
SH3PX1 Genome annotation
Ensembl GeneID KEGG UCSC
SH3PX1 Organism specific
CTD MGI
SH3PX1 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
SH3PX1 Gene expression
Bgee ArrayExpress Genevestigator
SH3PX1 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY