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Human Switch-associated protein 70 (aa 1-585 )

SWAP70 Swiss Prot#

Q9UH65

SWAP70 Protein names

Switch-associated protein 70 (SWAP-70)

SWAP70 Gene names

SWAP70 KIAA0640 HSPC321

Organism

Homo sapiens (Human)

SWAP70 Entry name

SWP70_HUMAN

SWAP70 Codon optimized cDNA(gene) Clone

SWAP70 Cat #

RPY1433

Tag

SWAP70 contains A 6x histidine tag

SWAP70 Formulation

Liquid

SWAP70 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

SWAP70 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant SWAP70 Protein

SWAP70 Cat #

PY1433

SWAP70 Source

recombinant

SWAP70 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

SWAP70 Purity

>90%, as determined by SDS-PAGE under reducing conditions

SWAP70 Activity

N/A

Tag

SWAP70 Contains A 6x histidine tag

SWAP70 Formulation

Liquid

SWAP70 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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SWAP70 family

-

SWAP70 Subcellular locations

Cytoplasm. Cell membrane. Nucleus. Cell projection > lamellipodium.

SWAP70 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Phosphatidylinositol 3,4,5-trisphosphate-dependent guanine nucleotide exchange factor (GEF) which, independently of RAS, transduces signals from tyrosine kinase receptors to RAC. It also mediates signaling of membrane ruffling. Regulates the actin cytoskeleton as an effector or adapter protein in response to agonist stimulated phosphatidylinositol (3,4)-bisphosphate production and cell protrusion (By similarity).

SWAP70 Sequence

DDBJ

EMBL

GenBank

SWAP70 3D structure

ModBase

SWAP70 interaction

STRING

SWAP70 Proteomic

PRIDE

SWAP70 Genome annotation

Ensembl

GeneID

KEGG

UCSC

SWAP70 Organism specific

CTD

MGI

SWAP70 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

SWAP70 Gene expression

Bgee

ArrayExpress

Genevestigator

SWAP70 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY