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Human Protein ajuba (aa 1-538 )

JUB Swiss Prot#

Q96IF1

JUB Protein names

Protein ajuba

JUB Gene names

JUB

Organism

Homo sapiens (Human)

JUB Entry name

JUB_HUMAN

JUB Codon optimized cDNA(gene) Clone

JUB Cat #

RPY1300

Tag

JUB contains A 6x histidine tag

JUB Formulation

Liquid

JUB Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

JUB Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant JUB Protein

JUB Cat #

PY1300

JUB Source

recombinant

JUB Applications

Western Blot, SDS-Page or may be used for other applications determined by user

JUB Purity

>90%, as determined by SDS-PAGE under reducing conditions

JUB Activity

N/A

Tag

JUB Contains A 6x histidine tag

JUB Formulation

Liquid

JUB Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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JUB family

Zyxin/ajuba family

JUB Subcellular locations

Cytoplasm > cytoskeleton. Cell membrane. Cell junction. Nucleus. Cytoplasm > cytoskeleton > centrosome.

JUB FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Components of cellular adhesives complexes. Contribute to cell fate determination and regulate cell proliferation and differentiation. Involved in the regulation of actin cytoskeleton dynamics and cell migration. Contributes to the linking and/or strengthening of epithelia cell-cell junctions in part by linking adhesive receptors to the actin cytoskeleton. May be involved in signal transduction from cell adhesion sites to the nucleus. Plays a important role in regulation of the kinase activity of AURKA/Aurora-A for mitotic commitment. Is also a component of the IL-1 signaling pathway modulating IL-1-induced NF-kappa-B activation by influencing the assembly and activity of the PRKCZ/SQSTM1/TRAF6 multiprotein signaling complex. Can functions as adapter molecules in the formation of large multiprotein complexes that form on DNA and that influence transcription.

JUB Sequence

DDBJ

EMBL

GenBank

JUB 3D structure

ModBase

JUB interaction

STRING

JUB Proteomic

PRIDE

JUB Genome annotation

Ensembl

GeneID

KEGG

UCSC

JUB Organism specific

CTD

MGI

JUB Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

JUB Gene expression

Bgee

ArrayExpress

Genevestigator

JUB Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY