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Mouse Cytoplasmic dynein 1 light intermediate chain 1 (aa 1-523 )

Dncli1 Swiss Prot#

Q8R1Q8

Dncli1 Protein names

Cytoplasmic dynein 1 light intermediate chain 1 (Dynein light chain A) (DLC-A) (Dynein light intermediate chain 1, cytosolic)

Dncli1 Gene names

Dync1li1 Dncli1 Dnclic1

Organism

Mus musculus (Mouse)

Dncli1 Entry name

DC1L1_MOUSE

Dncli1 Codon optimized cDNA(gene) Clone

Dncli1 Cat #

RPY1279

Tag

Dncli1 contains A 6x histidine tag

Dncli1 Formulation

Liquid

Dncli1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Dncli1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Dncli1 Protein

Dncli1 Cat #

PY1279

Dncli1 Source

recombinant

Dncli1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Dncli1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Dncli1 Activity

N/A

Tag

Dncli1 Contains A 6x histidine tag

Dncli1 Formulation

Liquid

Dncli1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Dncli1 family

Dynein light intermediate chain family

Dncli1 Subcellular locations

Cytoplasm. Chromosome > centromere > kinetochore. Cytoplasm > cytoskeleton > spindle pole.

Dncli1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Acts as one of several non-catalytic accessory components of the cytoplasmic dynein 1 complex that are thought to be involved in linking dynein to cargos and to adapter proteins that regulate dynein function. Cytoplasmic dynein 1 acts as a motor for the intracellular retrograde motility of vesicles and organelles along microtubules. May play a role in binding dynein to membranous organelles or chromosomes. Probably involved in the microtubule-dependent transport of pericentrin. Is required for progress throuh the spindle assembly checkpoint. The phosphorylated form appears to be involved in the selective removal of MAD1L1 and MAD1L2 but not BUB1B from kinetochores (By similarity).

Dncli1 Sequence

DDBJ

EMBL

GenBank

Dncli1 3D structure

ModBase

Dncli1 interaction

STRING

Dncli1 Proteomic

PRIDE

Dncli1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Dncli1 Organism specific

CTD

MGI

Dncli1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Dncli1 Gene expression

Bgee

ArrayExpress

Genevestigator

Dncli1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY