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Mouse Trichoplein keratin filament-binding protein (aa 1-497 )

Tchp Swiss Prot#

Q3TVW5

Tchp Protein names

Trichoplein keratin filament-binding protein (Protein TCHP) (Mitochondrial protein with oncostatic activity) (Mitostatin)

Tchp Gene names

Tchp

Organism

Mus musculus (Mouse)

Tchp Entry name

TCHP_MOUSE

Tchp Codon optimized cDNA(gene) Clone

Tchp Cat #

RPY1209

Tag

Tchp contains A 6x histidine tag

Tchp Formulation

Liquid

Tchp Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Tchp Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Tchp Protein

Tchp Cat #

PY1209

Tchp Source

recombinant

Tchp Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Tchp Purity

>90%, as determined by SDS-PAGE under reducing conditions

Tchp Activity

N/A

Tag

Tchp Contains A 6x histidine tag

Tchp Formulation

Liquid

Tchp Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Tchp family

TCHP family

Tchp Subcellular locations

Cytoplasm > cytoskeleton. Cytoplasm. Cell membrane. Mitochondrion.

Tchp FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Tumor suppressor which has the ability to inhibit cell growth and be pro-apoptotic during cell stress. May act as a 'capping' or 'branching' protein for keratin filaments in the cell periphery. May regulate K8/K18 filament and desmosome organization mainly at the apical or peripheral regions of simple epithelial cells (By similarity).

Tchp Sequence

DDBJ

EMBL

GenBank

Tchp 3D structure

ModBase

Tchp interaction

STRING

Tchp Proteomic

PRIDE

Tchp Genome annotation

Ensembl

GeneID

KEGG

UCSC

Tchp Organism specific

CTD

MGI

Tchp Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Tchp Gene expression

Bgee

ArrayExpress

Genevestigator

Tchp Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY