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Human DnaJ homolog subfamily C member 7 (aa 1-494 )
TPR2 Swiss Prot#
Q99615
TPR2 Protein names
DnaJ homolog subfamily C member 7 (Tetratricopeptide repeat protein 2) (TPR repeat protein 2)
TPR2 Gene names
DNAJC7 TPR2 TTC2
Organism
Homo sapiens (Human)
TPR2 Entry name
DNJC7_HUMAN
TPR2 Codon optimized cDNA(gene) Clone
TPR2 Cat #
RPY1201
Tag
TPR2 contains A 6x histidine tag
TPR2 Formulation
Liquid
TPR2 Storage
Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
TPR2 Applications
Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.
Recombinant TPR2 Protein
TPR2 Cat #
PY1201
TPR2 Source
recombinant
TPR2 Applications
Western Blot, SDS-Page or may be used for other applications determined by user
TPR2 Purity
>90%, as determined by SDS-PAGE under reducing conditions
TPR2 Activity
N/A
Tag
TPR2 Contains A 6x histidine tag
TPR2 Formulation
Liquid
TPR2 Storage
;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.
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TPR2 family
-
TPR2 Subcellular locations
Cytoplasm. Nucleus. Cytoplasm > cytoskeleton.
TPR2 FUNCTION According to UniProtKB Swiss Prot
FUNCTION: Acts as co-chaperone regulating the molecular chaperones HSP70 and HSP90 in folding of steroid receptors, such as the glucocorticoid receptor and the progesterone receptor. Proposed to act as a recycling chaperone by facilitating the return of chaperone substrates to early stages of chaperoning if further folding is required. In vitro, induces ATP-independent dissociation of HSP90 but not of HSP70 from the chaperone-substrate complexes. Recruits CXADR to the cytoplasm.
TPR2 Sequence
DDBJ EMBL GenBank
TPR2 3D structure
ModBase
TPR2 interaction
STRING
TPR2 Proteomic
PRIDE
TPR2 Genome annotation
Ensembl GeneID KEGG UCSC
TPR2 Organism specific
CTD MGI
TPR2 Phylogenomics
eggNOG GeneTree HOGENOM HOVERGEN

InParanoid OrthoDB PhylomeDB OMA
TPR2 Gene expression
Bgee ArrayExpress Genevestigator
TPR2 Family and domain
InterPro PROSITE ProtoNet
FOR in vitro RESEARCH USE ONLY