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Rat Katanin p60 ATPase-containing subunit A1 (aa 1-491 )

Katna1 Swiss Prot#

Q6E0V2

Katna1 Protein names

Katanin p60 ATPase-containing subunit A1 (Katanin p60 subunit A1) (EC 3.6.4.3) (p60 katanin)

Katna1 Gene names

Katna1

Organism

Rattus norvegicus (Rat)

Katna1 Entry name

KTNA1_RAT

Katna1 Codon optimized cDNA(gene) Clone

Katna1 Cat #

RPY1190

Tag

Katna1 contains A 6x histidine tag

Katna1 Formulation

Liquid

Katna1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Katna1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Katna1 Protein

Katna1 Cat #

PY1190

Katna1 Source

recombinant

Katna1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Katna1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Katna1 Activity

N/A

Tag

Katna1 Contains A 6x histidine tag

Katna1 Formulation

Liquid

Katna1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Katna1 family

AAA ATPase family

Katna1 Subcellular locations

Cytoplasm. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle pole.

Katna1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Severs microtubules in vitro in an ATP-dependent manner. This activity may promote rapid reorganization of cellular microtubule arrays, such as that seen during disassembly of interphase microtubules at the G2-M transition. May also be required for microtubule release from the centrosome after nucleation. In mitotic spindles this could allow depolymerization of the microtubule end proximal to the centrosome, and subsequent poleward microtubule flux. In neurons, microtubule release within the cell body allows their subsequent transport into neuronal processes by microtubule dependent motor proteins. This transport is required for axonal growth (By similarity).

Katna1 Sequence

DDBJ

EMBL

GenBank

Katna1 3D structure

ModBase

Katna1 interaction

STRING

Katna1 Proteomic

PRIDE

Katna1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Katna1 Organism specific

CTD

MGI

Katna1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Katna1 Gene expression

Bgee

ArrayExpress

Genevestigator

Katna1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY