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Human TNF receptor-associated factor 4 (aa 1-470 )

CART1 Swiss Prot#

Q9BUZ4

CART1 Protein names

TNF receptor-associated factor 4 (Cysteine-rich domain associated with RING and Traf domains protein 1) (Metastatic lymph node gene 62 protein) (MLN 62) (RING finger protein 83)

CART1 Gene names

TRAF4 CART1 MLN62 RNF83

Organism

Homo sapiens (Human)

CART1 Entry name

TRAF4_HUMAN

CART1 Codon optimized cDNA(gene) Clone

CART1 Cat #

RPY1125

Tag

CART1 contains A 6x histidine tag

CART1 Formulation

Liquid

CART1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CART1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CART1 Protein

CART1 Cat #

PY1125

CART1 Source

recombinant

CART1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CART1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

CART1 Activity

N/A

Tag

CART1 Contains A 6x histidine tag

CART1 Formulation

Liquid

CART1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CART1 family

TNF receptor-associated factor family, B subfamily

CART1 Subcellular locations

Cytoplasm. Nucleus. Cytoplasm > perinuclear region. Cell junction > tight junction. Cell membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasm > cytoskeleton.

CART1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Adapter protein and signal transducer that links members of the tumor necrosis factor receptor (TNFR) family to different signaling pathways. Plays a role in the activation of NF-kappa-B and JNK, and in the regulation of cell survival and apoptosis. Regulates activation of NF-kappa-B in response to signaling through Toll-like receptors. Required for normal skeleton development, and for normal development of the respiratory tract (By similarity). Required for activation of RPS6KB1 in response to TNF signaling. Modulates TRAF6 functions.

CART1 Sequence

DDBJ

EMBL

GenBank

CART1 3D structure

ModBase

CART1 interaction

STRING

CART1 Proteomic

PRIDE

CART1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

CART1 Organism specific

CTD

MGI

CART1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CART1 Gene expression

Bgee

ArrayExpress

Genevestigator

CART1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY