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Rat Peptidyl-prolyl cis-trans isomerase FKBP4 (aa 29-458 )

Fkbp52 Swiss Prot#

Q9QVC8

Fkbp52 Protein names

Peptidyl-prolyl cis-trans isomerase FKBP4 (PPIase FKBP4) (EC 5.2.1.8) (52 kDa FK506-binding protein) (52 kDa FKBP) (FKBP-52) (59 kDa immunophilin) (p59) (FK506-binding protein 4) (FKBP-4) (FKBP59) (HSP-binding immunophilin) (HBI) (Immunophilin FKBP52) (Rotamase) [Cleaved into: Peptidyl-prolyl cis-trans isomerase FKBP4, N-terminally processed]

Fkbp52 Gene names

Fkbp4 Fkbp52

Organism

Rattus norvegicus (Rat)

Fkbp52 Entry name

FKBP4_RAT

Fkbp52 Codon optimized cDNA(gene) Clone

Fkbp52 Cat #

RPY1088

Tag

Fkbp52 contains A 6x histidine tag

Fkbp52 Formulation

Liquid

Fkbp52 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Fkbp52 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Fkbp52 Protein

Fkbp52 Cat #

PY1088

Fkbp52 Source

recombinant

Fkbp52 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Fkbp52 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Fkbp52 Activity

N/A

Tag

Fkbp52 Contains A 6x histidine tag

Fkbp52 Formulation

Liquid

Fkbp52 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Fkbp52 family

-

Fkbp52 Subcellular locations

Cytoplasm > cytosol. Nucleus. Cytoplasm > cytoskeleton.

Fkbp52 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Immunophilin protein with PPIase and co-chaperone activities (By similarity). Component of unliganded steroid receptors heterocomplexes through interaction with heat-shock protein 90 (HSP90) (By similarity). Play a role in the intracellular trafficking of heterooligomeric forms of steroid hormone receptors between cytoplasm and nuclear compartments (By similarity). Acts also as a regulator of microtubule dynamics by inhibiting MAPT/TAU ability to promote microtubule assembly. The PPIase activity controls neuronal growth cones via regulation of TRPC1 channel opening.

Fkbp52 Sequence

DDBJ

EMBL

GenBank

Fkbp52 3D structure

ModBase

Fkbp52 interaction

STRING

Fkbp52 Proteomic

PRIDE

Fkbp52 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Fkbp52 Organism specific

CTD

MGI

Fkbp52 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Fkbp52 Gene expression

Bgee

ArrayExpress

Genevestigator

Fkbp52 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY