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Human Alpha-2A adrenergic receptor (aa 1-450 )

ADRA2R Swiss Prot#

P08913

ADRA2R Protein names

Alpha-2A adrenergic receptor (Alpha-2 adrenergic receptor subtype C10) (Alpha-2A adrenoreceptor) (Alpha-2A adrenoceptor) (Alpha-2AAR)

ADRA2R Gene names

ADRA2A ADRA2R ADRAR

Organism

Homo sapiens (Human)

ADRA2R Entry name

ADA2A_HUMAN

ADRA2R Codon optimized cDNA(gene) Clone

ADRA2R Cat #

RPY1052

Tag

ADRA2R contains A 6x histidine tag

ADRA2R Formulation

Liquid

ADRA2R Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

ADRA2R Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant ADRA2R Protein

ADRA2R Cat #

PY1052

ADRA2R Source

recombinant

ADRA2R Applications

Western Blot, SDS-Page or may be used for other applications determined by user

ADRA2R Purity

>90%, as determined by SDS-PAGE under reducing conditions

ADRA2R Activity

N/A

Tag

ADRA2R Contains A 6x histidine tag

ADRA2R Formulation

Liquid

ADRA2R Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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ADRA2R family

G-protein coupled receptor 1 family, Adrenergic receptor subfamily, ADRA2A sub-subfamily

ADRA2R Subcellular locations

Cell membrane; Multi-pass membrane protein.

ADRA2R FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Alpha-2 adrenergic receptors mediate the catecholamine-induced inhibition of adenylate cyclase through the action of G proteins. The rank order of potency for agonists of this receptor is oxymetazoline > clonidine > epinephrine > norepinephrine > phenylephrine > dopamine > p-synephrine > p-tyramine > serotonin = p-octopamine. For antagonists, the rank order is yohimbine > phentolamine = mianserine > chlorpromazine = spiperone = prazosin > propanolol > alprenolol = pindolol.

ADRA2R Sequence

DDBJ

EMBL

GenBank

ADRA2R 3D structure

ModBase

ADRA2R interaction

STRING

ADRA2R Proteomic

PRIDE

ADRA2R Genome annotation

Ensembl

GeneID

KEGG

UCSC

ADRA2R Organism specific

CTD

MGI

ADRA2R Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

ADRA2R Gene expression

Bgee

ArrayExpress

Genevestigator

ADRA2R Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY