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Mouse Phosphoprotein associated glycosphingolipid-enriched 1 (aa 24-429 )

Cbp Swiss Prot#

Q3U1F9

Cbp Protein names

Phosphoprotein associated with glycosphingolipid-enriched microdomains 1 (Csk-binding protein) (Transmembrane phosphoprotein Cbp)

Cbp Gene names

Pag1 Cbp Pag

Organism

Mus musculus (Mouse)

Cbp Entry name

PAG1_MOUSE

Cbp Codon optimized cDNA(gene) Clone

Cbp Cat #

RPY0963

Tag

Cbp contains A 6x histidine tag

Cbp Formulation

Liquid

Cbp Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Cbp Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Cbp Protein

Cbp Cat #

PY0963

Cbp Source

recombinant

Cbp Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Cbp Purity

>90%, as determined by SDS-PAGE under reducing conditions

Cbp Activity

N/A

Tag

Cbp Contains A 6x histidine tag

Cbp Formulation

Liquid

Cbp Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Cbp family

-

Cbp Subcellular locations

Cell membrane; Single-pass type III membrane protein.

Cbp FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Negatively regulates TCR (T-cell antigen receptor)-mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor)-mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.

Cbp Sequence

DDBJ

EMBL

GenBank

Cbp 3D structure

ModBase

Cbp interaction

STRING

Cbp Proteomic

PRIDE

Cbp Genome annotation

Ensembl

GeneID

KEGG

UCSC

Cbp Organism specific

CTD

MGI

Cbp Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Cbp Gene expression

Bgee

ArrayExpress

Genevestigator

Cbp Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY