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Rat Ras association domain-containing protein 5 (aa 54-413 )

Nore1 Swiss Prot#

O35141

Nore1 Protein names

Ras association domain-containing protein 5 (Maxp1) (New ras effector 1)

Nore1 Gene names

Rassf5 Nore1

Organism

Rattus norvegicus (Rat)

Nore1 Entry name

RASF5_RAT

Nore1 Codon optimized cDNA(gene) Clone

Nore1 Cat #

RPY0895

Tag

Nore1 contains A 6x histidine tag

Nore1 Formulation

Liquid

Nore1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Nore1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Nore1 Protein

Nore1 Cat #

PY0895

Nore1 Source

recombinant

Nore1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Nore1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Nore1 Activity

N/A

Tag

Nore1 Contains A 6x histidine tag

Nore1 Formulation

Liquid

Nore1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Nore1 family

-

Nore1 Subcellular locations

Cytoplasm. Cytoplasm > cytoskeleton.

Nore1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Potential tumor suppressor. Seems to be involved in lymphocyte adhesion by linking RAP1A activation upon T cell receptor or chemokine stimulation to integrin activation. Stimulates lymphocyte polarization and the patch-like distribution of ITGAL/LFA-1, resulting in an enhanced adhesion to ICAM1. Together with RAP1A may participate in regulation of microtubule growth. The association with activated RAP1A is required for directional movement of endothelial cells during wound healing. May be involved in regulation of Ras apoptotic function. The RASSF5-STK4 complex may mediate HRAS1 and KRAS induced apoptosis (By similarity).

Nore1 Sequence

DDBJ

EMBL

GenBank

Nore1 3D structure

ModBase

Nore1 interaction

STRING

Nore1 Proteomic

PRIDE

Nore1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Nore1 Organism specific

CTD

MGI

Nore1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Nore1 Gene expression

Bgee

ArrayExpress

Genevestigator

Nore1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY