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Mouse Spindle kinetochore-associated protein 3 (aa 1-411 )

Rama1 Swiss Prot#

Q8C263

Rama1 Protein names

Spindle and kinetochore-associated protein 3

Rama1 Gene names

Ska3 Rama1

Organism

Mus musculus (Mouse)

Rama1 Entry name

SKA3_MOUSE

Rama1 Codon optimized cDNA(gene) Clone

Rama1 Cat #

RPY0886

Tag

Rama1 contains A 6x histidine tag

Rama1 Formulation

Liquid

Rama1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Rama1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Rama1 Protein

Rama1 Cat #

PY0886

Rama1 Source

recombinant

Rama1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Rama1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Rama1 Activity

N/A

Tag

Rama1 Contains A 6x histidine tag

Rama1 Formulation

Liquid

Rama1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Rama1 family

SKA3 family

Rama1 Subcellular locations

Cytoplasm > cytoskeleton > spindle. Chromosome > centromere > kinetochore.

Rama1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Component of the SKA1 complex, a microtubule-binding subcomplex of the outer kinetochore that is essential for proper chromosome segregation. The SKA1 complex is a direct component of the kinetochore-microtubule interface and directly associates with microtubules as oligomeric assemblies. The complex facilitates the processive movement of microspheres along a microtubule in a depolymerization-coupled manner. In the complex, it mediates the microtubule-stimulated oligomerization (By similarity).

Rama1 Sequence

DDBJ

EMBL

GenBank

Rama1 3D structure

ModBase

Rama1 interaction

STRING

Rama1 Proteomic

PRIDE

Rama1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Rama1 Organism specific

CTD

MGI

Rama1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Rama1 Gene expression

Bgee

ArrayExpress

Genevestigator

Rama1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY