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Mouse Angiopoietin-related protein 4 (aa 23-410 )

Farp Swiss Prot#

Q9Z1P8

Farp Protein names

Angiopoietin-related protein 4 (425O18-1) (Angiopoietin-like protein 4) (Fasting-induced adipose factor) (Hepatic fibrinogen/angiopoietin-related protein) (HFARP) (Secreted protein Bk89)

Farp Gene names

Angptl4 Farp Fiaf Ng27

Organism

Mus musculus (Mouse)

Farp Entry name

ANGL4_MOUSE

Farp Codon optimized cDNA(gene) Clone

Farp Cat #

RPY0878

Tag

Farp contains A 6x histidine tag

Farp Formulation

Liquid

Farp Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Farp Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Farp Protein

Farp Cat #

PY0878

Farp Source

recombinant

Farp Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Farp Purity

>90%, as determined by SDS-PAGE under reducing conditions

Farp Activity

N/A

Tag

Farp Contains A 6x histidine tag

Farp Formulation

Liquid

Farp Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Farp family

-

Farp Subcellular locations

Secreted. Secreted > extracellular space > extracellular matrix.

Farp FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Protein with hypoxia-induced expression in endothelial cells. May act as a regulator of angiogenesis and modulate tumorgenesis. Inhibits proliferation, migration, and tubule formation of endothelial cells and reduces vascular leakage. May exert a protective function on endothelial cells through an endocrine action. It is directly involved in regulating glucose homeostasis, lipid metabolism, and insulin sensitivity (By similarity). In response to hypoxia, the unprocessed form of the protein accumulates in the subendothelial extracellular matrix (ECM). The matrix-associated and immobilized unprocessed form limits the formation of actin stress fibers and focal contacts in the adhering endothelial cells and inhibits their adhesion. It also decreases motility of endothelial cells and inhibits the sprouting and tube formation.

Farp Sequence

DDBJ

EMBL

GenBank

Farp 3D structure

ModBase

Farp interaction

STRING

Farp Proteomic

PRIDE

Farp Genome annotation

Ensembl

GeneID

KEGG

UCSC

Farp Organism specific

CTD

MGI

Farp Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Farp Gene expression

Bgee

ArrayExpress

Genevestigator

Farp Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY