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Rat Pleckstrin homology domain-containing family O 1 (aa 1-408 )

Plekho1 Swiss Prot#

Q5BJM5

Plekho1 Protein names

Pleckstrin homology domain-containing family O member 1 (PH domain-containing family O member 1)

Plekho1 Gene names

Plekho1

Organism

Rattus norvegicus (Rat)

Plekho1 Entry name

PKHO1_RAT

Plekho1 Codon optimized cDNA(gene) Clone

Plekho1 Cat #

RPY0875

Tag

Plekho1 contains A 6x histidine tag

Plekho1 Formulation

Liquid

Plekho1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Plekho1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Plekho1 Protein

Plekho1 Cat #

PY0875

Plekho1 Source

recombinant

Plekho1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Plekho1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Plekho1 Activity

N/A

Tag

Plekho1 Contains A 6x histidine tag

Plekho1 Formulation

Liquid

Plekho1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Plekho1 family

-

Plekho1 Subcellular locations

Membrane. Nucleus. Cytoplasm.

Plekho1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Plays a role in the regulation of the actin cytoskeleton through its interactions with actin capping protein (CP). May function to target CK2 to the plasma membrane thereby serving as an adapter to facilitate the phosphorylation of CP by protein kinase 2 (CK2). Appears to target ATM to the plasma membrane. Also implicated in PI3K-regulated muscle differentiation, the regulation of AP-1 activity (plasma membrane bound AP-1 regulator that translocates to the nucleus) and the promotion of apoptosis induced by tumor necrosis factor TNF. When bound to PKB, it inhibits it probably by decreasing PKB level of phosphorylation (By similarity).

Plekho1 Sequence

DDBJ

EMBL

GenBank

Plekho1 3D structure

ModBase

Plekho1 interaction

STRING

Plekho1 Proteomic

PRIDE

Plekho1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Plekho1 Organism specific

CTD

MGI

Plekho1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Plekho1 Gene expression

Bgee

ArrayExpress

Genevestigator

Plekho1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY