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Rat Activity-regulated cytoskeleton-associated protein (aa 36-396 )

Arc Swiss Prot#

Q63053

Arc Protein names

Activity-regulated cytoskeleton-associated protein (ARC/ARG3.1) (Activity-regulated gene 3.1 protein) (Arg3.1)

Arc Gene names

Arc

Organism

Rattus norvegicus (Rat)

Arc Entry name

ARC_RAT

Arc Codon optimized cDNA(gene) Clone

Arc Cat #

RPY0850

Tag

Arc contains A 6x histidine tag

Arc Formulation

Liquid

Arc Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Arc Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Arc Protein

Arc Cat #

PY0850

Arc Source

recombinant

Arc Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Arc Purity

>90%, as determined by SDS-PAGE under reducing conditions

Arc Activity

N/A

Tag

Arc Contains A 6x histidine tag

Arc Formulation

Liquid

Arc Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Arc family

ARC/ARG3.1 family

Arc Subcellular locations

Cytoplasm > cytoskeleton. Endosome. Cytoplasmic vesicle > secretory vesicle > acrosome. Cytoplasm > cell cortex. Cell projection > dendrite. Cell projection > dendritic spine. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cell junction > synapse.

Arc FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Required for consolidation of synaptic plasticity as well as formation of long-term memory. Regulates endocytosis of AMPA receptors in response to synaptic activity. Required for homeostatic synaptic scaling of AMPA receptors.

Arc Sequence

DDBJ

EMBL

GenBank

Arc 3D structure

ModBase

Arc interaction

STRING

Arc Proteomic

PRIDE

Arc Genome annotation

Ensembl

GeneID

KEGG

UCSC

Arc Organism specific

CTD

MGI

Arc Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Arc Gene expression

Bgee

ArrayExpress

Genevestigator

Arc Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY