|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
|
|
||||||||||||||||||||||||||||||||||
|
|||||||||||||
|
|||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Human Vasodilator-stimulated phosphoprotein (aa 1-380 ) |
| VASP Swiss Prot# | | P50552 |
| VASP Protein names | | Vasodilator-stimulated phosphoprotein (VASP) |
| VASP Gene names | | VASP |
| Organism | | Homo sapiens (Human) |
| VASP Entry name | | VASP_HUMAN |
| VASP Codon optimized cDNA(gene) Clone |
| VASP Cat # | | RPY0808 |
| Tag | | VASP contains A 6x histidine tag |
| VASP Formulation | | Liquid |
| VASP Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| VASP Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant VASP Protein |
| VASP Cat # | | PY0808 |
| VASP Source | | recombinant |
| VASP Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| VASP Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| VASP Activity | | N/A |
| Tag | | VASP Contains A 6x histidine tag |
| VASP Formulation | | Liquid |
| VASP Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant VASP Products | | For pricing and availability Click Here >>> |
| VASP family | | Ena/VASP family |
| VASP Subcellular locations | | Cytoplasm. Cytoplasm > cytoskeleton. Cell junction > focal adhesion. Cell projection > lamellipodium membrane. Cell projection > filopodium membrane. |
| VASP FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: Ena/VASP proteins are actin-associated proteins involved in a range of processes dependent on cytoskeleton remodeling and cell polarity such as axon guidance, lamellipodial and filopodial dynamics, platelet activation and cell migration. VASP promotes actin filament elongation. It protects the barbed end of growing actin filaments against capping and increases the rate of actin polymerization in the presence of capping protein. VASP stimulates actin filament elongation by promoting the transfer of profilin-bound actin monomers onto the barbed end of growing actin filaments. Plays a role in actin-based mobility of Listeria monocytogenes in host cells. Regulates actin dynamics in platelets and plays an important role in regulating platelet aggregation. |
| VASP Sequence | | DDBJ | EMBL | GenBank |
| VASP 3D structure | | ModBase |
| VASP interaction | | STRING |
| VASP Proteomic | | PRIDE |
| VASP Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| VASP Organism specific | | CTD | MGI |
| VASP Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| VASP Gene expression | | Bgee | ArrayExpress | Genevestigator |
| VASP Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |