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Human Transcription factor NF-E2 45 kDa subunit (aa 41-373 )

NFE2 Swiss Prot#

Q16621

NFE2 Protein names

Transcription factor NF-E2 45 kDa subunit (Leucine zipper protein NF-E2) (Nuclear factor, erythroid-derived 2 45 kDa subunit) (p45 NF-E2)

NFE2 Gene names

NFE2

Organism

Homo sapiens (Human)

NFE2 Entry name

NFE2_HUMAN

NFE2 Codon optimized cDNA(gene) Clone

NFE2 Cat #

RPY0779

Tag

NFE2 contains A 6x histidine tag

NFE2 Formulation

Liquid

NFE2 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

NFE2 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant NFE2 Protein

NFE2 Cat #

PY0779

NFE2 Source

recombinant

NFE2 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

NFE2 Purity

>90%, as determined by SDS-PAGE under reducing conditions

NFE2 Activity

N/A

Tag

NFE2 Contains A 6x histidine tag

NFE2 Formulation

Liquid

NFE2 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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NFE2 family

BZIP family, CNC subfamily

NFE2 Subcellular locations

Nucleus > PML body. Cytoplasm.

NFE2 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Component of the NF-E2 complex essential for regulating erythroid and megakaryocytic maturation and differentiation. Binds to the hypersensitive site 2 (HS2) of the beta-globin control region (LCR). This subunit (NFE2) recognizes the TCAT/C sequence of the AP-1-like core palindrome present in a number of erythroid and megakaryocytic gene promoters. Requires MAFK or other small MAF proteins for binding to the NF-E2 motif. May play a role in all aspects of hemoglobin production from globin and heme synthesis to procurement of iron.

NFE2 Sequence

DDBJ

EMBL

GenBank

NFE2 3D structure

ModBase

NFE2 interaction

STRING

NFE2 Proteomic

PRIDE

NFE2 Genome annotation

Ensembl

GeneID

KEGG

UCSC

NFE2 Organism specific

CTD

MGI

NFE2 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

NFE2 Gene expression

Bgee

ArrayExpress

Genevestigator

NFE2 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY