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Human Calcium-binding protein 1 (aa 1-370 )

CABP1 Swiss Prot#

Q9NZU7

CABP1 Protein names

Calcium-binding protein 1 (CaBP1) (Calbrain) (Caldendrin)

CABP1 Gene names

CABP1

Organism

Homo sapiens (Human)

CABP1 Entry name

CABP1_HUMAN

CABP1 Codon optimized cDNA(gene) Clone

CABP1 Cat #

RPY0762

Tag

CABP1 contains A 6x histidine tag

CABP1 Formulation

Liquid

CABP1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

CABP1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant CABP1 Protein

CABP1 Cat #

PY0762

CABP1 Source

recombinant

CABP1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

CABP1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

CABP1 Activity

N/A

Tag

CABP1 Contains A 6x histidine tag

CABP1 Formulation

Liquid

CABP1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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CABP1 family

-

CABP1 Subcellular locations

Cytoplasm > cytoskeleton. Cytoplasm > perinuclear region. Cell membrane; Lipid-anchor; Cytoplasmic side. Golgi apparatus. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Cytoplasm > cytoskeleton. Cytoplasm > cell cortex. Cell membrane; Lipid-anchor.

CABP1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Modulates calcium-dependent activity of inositol 1,4,5-triphosphate receptors (ITPRs). Inhibits agonist-induced intracellular calcium signaling. Enhances inactivation and does not support calcium-dependent facilitation of voltage-dependent P/Q-type calcium channels. Causes calcium-dependent facilitation and inhibits inactivation of L-type calcium channels by binding to the same sites as calmodulin in the C-terminal domain of CACNA1C, but resulting in an opposit effects on channel function. Suppresses the calcium-dependent inactivation of CACNA1D (By similarity). Inhibits TRPC5 channels. Prevents NMDA receptor-induced cellular degeneration (By similarity).

CABP1 Sequence

DDBJ

EMBL

GenBank

CABP1 3D structure

ModBase

CABP1 interaction

STRING

CABP1 Proteomic

PRIDE

CABP1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

CABP1 Organism specific

CTD

MGI

CABP1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

CABP1 Gene expression

Bgee

ArrayExpress

Genevestigator

CABP1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY