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Mouse Septin-2 (aa 1-361 )

Nedd-5 Swiss Prot#

P42208

Nedd-5 Protein names

Septin-2 (Neural precursor cell expressed developmentally down-regulated protein 5) (NEDD-5)

Nedd-5 Gene names

Sept2 Nedd-5 Nedd5

Organism

Mus musculus (Mouse)

Nedd-5 Entry name

SEPT2_MOUSE

Nedd-5 Codon optimized cDNA(gene) Clone

Nedd-5 Cat #

RPY0728

Tag

Nedd-5 contains A 6x histidine tag

Nedd-5 Formulation

Liquid

Nedd-5 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Nedd-5 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Nedd-5 Protein

Nedd-5 Cat #

PY0728

Nedd-5 Source

recombinant

Nedd-5 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Nedd-5 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Nedd-5 Activity

N/A

Tag

Nedd-5 Contains A 6x histidine tag

Nedd-5 Formulation

Liquid

Nedd-5 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Nedd-5 family

Septin family

Nedd-5 Subcellular locations

Cytoplasm. Cytoplasm > cytoskeleton. Cytoplasm > cytoskeleton > spindle. Chromosome > centromere > kinetochore. Cleavage furrow. Midbody.

Nedd-5 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Filament-forming cytoskeletal GTPase. Required for normal organization of the actin cytoskeleton. Plays a role in the biogenesis of polarized columnar-shaped epithelium. Required for the progression through mitosis. Forms a scaffold at the midplane of the mitotic splindle required to maintain CENPE localization at kinetochores and consequently chromosome congression. During anaphase, may be required for chromosome segregation and spindle elongation (By similarity).

Nedd-5 Sequence

DDBJ

EMBL

GenBank

Nedd-5 3D structure

ModBase

Nedd-5 interaction

STRING

Nedd-5 Proteomic

PRIDE

Nedd-5 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Nedd-5 Organism specific

CTD

MGI

Nedd-5 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Nedd-5 Gene expression

Bgee

ArrayExpress

Genevestigator

Nedd-5 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY