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Human Dysbindin (aa 1-351 )

My031 Swiss Prot#

Q96EV8

My031 Protein names

Dysbindin (Dysbindin-1) (Dystrobrevin-binding protein 1) (Hermansky-Pudlak syndrome 7 protein) (HPS7 protein)

My031 Gene names

DTNBP1 My031

Organism

Homo sapiens (Human)

My031 Entry name

DTBP1_HUMAN

My031 Codon optimized cDNA(gene) Clone

My031 Cat #

RPY0688

Tag

My031 contains A 6x histidine tag

My031 Formulation

Liquid

My031 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

My031 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant My031 Protein

My031 Cat #

PY0688

My031 Source

recombinant

My031 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

My031 Purity

>90%, as determined by SDS-PAGE under reducing conditions

My031 Activity

N/A

Tag

My031 Contains A 6x histidine tag

My031 Formulation

Liquid

My031 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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My031 family

Dysbindin family

My031 Subcellular locations

Cytoplasm. Cytoplasmic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Cytoplasmic vesicle > secretory vesicle > synaptic vesicle membrane; Peripheral membrane protein; Cytoplasmic side. Endosome membrane; Peripheral membrane protein; Cytoplasmic side. Melanosome membrane; Peripheral membrane protein; Cytoplasmic side. Nucleus. Cell junction > synapse > postsynaptic cell membrane > postsynaptic density. Endoplasmic reticulum.

My031 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: The BLOC-1 complex is required for normal biogenesis of lysosome-related organelles, such as platelet dense granules and melanosomes. Plays a role in intracellular vesicle trafficking. Plays a role in synaptic vesicle trafficking and in neurotransmitter release. May be required for normal dopamine homeostasis in the cerebral cortex, hippocampus, and hypothalamus. Plays a role in the regulation of cell surface exposure of DRD2. Contributes to the regulation of dopamine signaling. May play a role in actin cytoskeleton reorganization and neurite outgrowth. May modulate MAPK8 phosphorylation.

My031 Sequence

DDBJ

EMBL

GenBank

My031 3D structure

ModBase

My031 interaction

STRING

My031 Proteomic

PRIDE

My031 Genome annotation

Ensembl

GeneID

KEGG

UCSC

My031 Organism specific

CTD

MGI

My031 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

My031 Gene expression

Bgee

ArrayExpress

Genevestigator

My031 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY