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Rat Nuclear distribution protein nudE homolog 1 (aa 1-344 )

Nude Swiss Prot#

Q9ES39

Nude Protein names

Nuclear distribution protein nudE homolog 1 (NudE) (rNudE)

Nude Gene names

Nde1 Nude Nude1

Organism

Rattus norvegicus (Rat)

Nude Entry name

NDE1_RAT

Nude Codon optimized cDNA(gene) Clone

Nude Cat #

RPY0660

Tag

Nude contains A 6x histidine tag

Nude Formulation

Liquid

Nude Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Nude Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Nude Protein

Nude Cat #

PY0660

Nude Source

recombinant

Nude Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Nude Purity

>90%, as determined by SDS-PAGE under reducing conditions

Nude Activity

N/A

Tag

Nude Contains A 6x histidine tag

Nude Formulation

Liquid

Nude Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Nude family

NudE family

Nude Subcellular locations

Cytoplasm > cytoskeleton. Cytoplasm > cytoskeleton > centrosome. Cytoplasm > cytoskeleton > spindle. Chromosome > centromere > kinetochore. Cleavage furrow.

Nude FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Required for centrosome duplication and formation and function of the mitotic spindle. Essential for the development of the cerebral cortex. May regulate the production of neurons by controlling the orientation of the mitotic spindle during division of cortical neuronal progenitors of the proliferative ventricular zone of the brain. Orientation of the division plane perpendicular to the layers of the cortex gives rise to two proliferative neuronal progenitors whereas parallel orientation of the division plane yields one proliferative neuronal progenitor and a post-mitotic neuron. A premature shift towards a neuronal fate within the progenitor population may result in an overall reduction in the final number of neurons and an increase in the number of neurons in the deeper layers of the cortex (By similarity).

Nude Sequence

DDBJ

EMBL

GenBank

Nude 3D structure

ModBase

Nude interaction

STRING

Nude Proteomic

PRIDE

Nude Genome annotation

Ensembl

GeneID

KEGG

UCSC

Nude Organism specific

CTD

MGI

Nude Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Nude Gene expression

Bgee

ArrayExpress

Genevestigator

Nude Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY