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Mouse Bardet-Biedl syndrome 5 protein homolog (aa 1-341 )

Bbs5 Swiss Prot#

Q9CZQ9

Bbs5 Protein names

Bardet-Biedl syndrome 5 protein homolog

Bbs5 Gene names

Bbs5

Organism

Mus musculus (Mouse)

Bbs5 Entry name

BBS5_MOUSE

Bbs5 Codon optimized cDNA(gene) Clone

Bbs5 Cat #

RPY0653

Tag

Bbs5 contains A 6x histidine tag

Bbs5 Formulation

Liquid

Bbs5 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Bbs5 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Bbs5 Protein

Bbs5 Cat #

PY0653

Bbs5 Source

recombinant

Bbs5 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Bbs5 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Bbs5 Activity

N/A

Tag

Bbs5 Contains A 6x histidine tag

Bbs5 Formulation

Liquid

Bbs5 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Bbs5 family

BBS5 family

Bbs5 Subcellular locations

Cell projection > cilium membrane. Cytoplasm. Cytoplasm > cytoskeleton > cilium basal body.

Bbs5 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: The BBSome complex is required for ciliogenesis but is dispensable for centriolar satellite function. This ciliogenic function is mediated in part by the Rab8 GDP/GTP exchange factor, which localizes to the basal body and contacts the BBSome. Rab8(GTP) enters the primary cilium and promotes extension of the ciliary membrane. Firstly the BBSome associates with the ciliary membrane and binds to Rabin8, the guanosyl exchange factor (GEF) for Rab8 and then the Rab8-GTP localizes to the cilium and promotes docking and fusion of carrier vesicles to the base of the ciliary membrane (By similarity).

Bbs5 Sequence

DDBJ

EMBL

GenBank

Bbs5 3D structure

ModBase

Bbs5 interaction

STRING

Bbs5 Proteomic

PRIDE

Bbs5 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Bbs5 Organism specific

CTD

MGI

Bbs5 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Bbs5 Gene expression

Bgee

ArrayExpress

Genevestigator

Bbs5 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY