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Mouse BTB POZ domain-containing adapter CUL3 (aa 1-329 )

Poldip1 Swiss Prot#

Q8BGV7

Poldip1 Protein names

BTB/POZ domain-containing adapter for CUL3-mediated RhoA degradation protein 1 (BTB/POZ domain-containing protein KCTD13) (Polymerase delta-interacting protein 1)

Poldip1 Gene names

Kctd13 Poldip1

Organism

Mus musculus (Mouse)

Poldip1 Entry name

BACD1_MOUSE

Poldip1 Codon optimized cDNA(gene) Clone

Poldip1 Cat #

RPY0615

Tag

Poldip1 contains A 6x histidine tag

Poldip1 Formulation

Liquid

Poldip1 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Poldip1 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Poldip1 Protein

Poldip1 Cat #

PY0615

Poldip1 Source

recombinant

Poldip1 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Poldip1 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Poldip1 Activity

N/A

Tag

Poldip1 Contains A 6x histidine tag

Poldip1 Formulation

Liquid

Poldip1 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Poldip1 family

BACURD family

Poldip1 Subcellular locations

Nucleus.

Poldip1 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex involved in regulation of cytoskeleton structure. The BCR(BACURD1) E3 ubiquitin ligase complex mediates the ubiquitination of RHOA, leading to its degradation by the proteasome, thereby regulating the actin cytoskeleton and cell migration (By similarity).

Poldip1 Sequence

DDBJ

EMBL

GenBank

Poldip1 3D structure

ModBase

Poldip1 interaction

STRING

Poldip1 Proteomic

PRIDE

Poldip1 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Poldip1 Organism specific

CTD

MGI

Poldip1 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Poldip1 Gene expression

Bgee

ArrayExpress

Genevestigator

Poldip1 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY