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| Human Adapter molecule crk (aa 1-304 ) |
| CRK Swiss Prot# | | P46108 |
| CRK Protein names | | Adapter molecule crk (Proto-oncogene c-Crk) (p38) |
| CRK Gene names | | CRK |
| Organism | | Homo sapiens (Human) |
| CRK Entry name | | CRK_HUMAN |
| CRK Codon optimized cDNA(gene) Clone |
| CRK Cat # | | RPY0545 |
| Tag | | CRK contains A 6x histidine tag |
| CRK Formulation | | Liquid |
| CRK Storage | | Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| CRK Applications | | Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function. |
| Recombinant CRK Protein |
| CRK Cat # | | PY0545 |
| CRK Source | | recombinant |
| CRK Applications | | Western Blot, SDS-Page or may be used for other applications determined by user |
| CRK Purity | | >90%, as determined by SDS-PAGE under reducing conditions |
| CRK Activity | | N/A |
| Tag | | CRK Contains A 6x histidine tag |
| CRK Formulation | | Liquid |
| CRK Storage | | ;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles. |
| Place Order for Recombinant CRK Products | | For pricing and availability Click Here >>> |
| CRK family | | CRK family |
| CRK Subcellular locations | | Cytoplasm. Cell membrane. |
| CRK FUNCTION According to UniProtKB Swiss Prot | | FUNCTION: The Crk-I and Crk-II forms differ in their biological activities. Crk-II has less transforming activity than Crk-I. Crk-II mediates attachment-induced MAPK8 activation, membrane ruffling and cell motility in a Rac-dependent manner. Involved in phagocytosis of apoptotic cells and cell motility via its interaction with DOCK1 and DOCK4. |
| CRK Sequence | | DDBJ | EMBL | GenBank |
| CRK 3D structure | | ModBase |
| CRK interaction | | STRING |
| CRK Proteomic | | PRIDE |
| CRK Genome annotation | | Ensembl | GeneID | KEGG | UCSC |
| CRK Organism specific | | CTD | MGI |
| CRK Phylogenomics | | eggNOG | GeneTree | HOGENOM | HOVERGEN |
| | InParanoid | OrthoDB | PhylomeDB | OMA |
| CRK Gene expression | | Bgee | ArrayExpress | Genevestigator |
| CRK Family and domain | | InterPro | PROSITE | ProtoNet |
| FOR in vitro RESEARCH USE ONLY |