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Human Borealin (aa 1-280 )

PESCRG3 Swiss Prot#

Q53HL2

PESCRG3 Protein names

Borealin (Cell division cycle-associated protein 8) (Dasra-B) (hDasra-B) (Pluripotent embryonic stem cell-related gene 3 protein)

PESCRG3 Gene names

CDCA8 PESCRG3

Organism

Homo sapiens (Human)

PESCRG3 Entry name

BOREA_HUMAN

PESCRG3 Codon optimized cDNA(gene) Clone

PESCRG3 Cat #

RPY0460

Tag

PESCRG3 contains A 6x histidine tag

PESCRG3 Formulation

Liquid

PESCRG3 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

PESCRG3 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant PESCRG3 Protein

PESCRG3 Cat #

PY0460

PESCRG3 Source

recombinant

PESCRG3 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

PESCRG3 Purity

>90%, as determined by SDS-PAGE under reducing conditions

PESCRG3 Activity

N/A

Tag

PESCRG3 Contains A 6x histidine tag

PESCRG3 Formulation

Liquid

PESCRG3 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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PESCRG3 family

Borealin family

PESCRG3 Subcellular locations

Nucleus > nucleolus. Cytoplasm. Cytoplasm > cytoskeleton > spindle. Chromosome > centromere.

PESCRG3 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Component of the chromosomal passenger complex (CPC), a complex that acts as a key regulator of mitosis. The CPC complex has essential functions at the centromere in ensuring correct chromosome alignment and segregation and is required for chromatin-induced microtubule stabilization and spindle assembly. In the complex, it may be required to direct the CPC to centromeric DNA. Major effector of the TTK kinase in the control of attachment-error-correction and chromosome alignment.

PESCRG3 Sequence

DDBJ

EMBL

GenBank

PESCRG3 3D structure

ModBase

PESCRG3 interaction

STRING

PESCRG3 Proteomic

PRIDE

PESCRG3 Genome annotation

Ensembl

GeneID

KEGG

UCSC

PESCRG3 Organism specific

CTD

MGI

PESCRG3 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

PESCRG3 Gene expression

Bgee

ArrayExpress

Genevestigator

PESCRG3 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY