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Human Transcription factor Spi-B (aa 29-262 )

SPIB Swiss Prot#

Q01892

SPIB Protein names

Transcription factor Spi-B

SPIB Gene names

SPIB

Organism

Homo sapiens (Human)

SPIB Entry name

SPIB_HUMAN

SPIB Codon optimized cDNA(gene) Clone

SPIB Cat #

RPY0416

Tag

SPIB contains A 6x histidine tag

SPIB Formulation

Liquid

SPIB Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

SPIB Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant SPIB Protein

SPIB Cat #

PY0416

SPIB Source

recombinant

SPIB Applications

Western Blot, SDS-Page or may be used for other applications determined by user

SPIB Purity

>90%, as determined by SDS-PAGE under reducing conditions

SPIB Activity

N/A

Tag

SPIB Contains A 6x histidine tag

SPIB Formulation

Liquid

SPIB Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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SPIB family

ETS family

SPIB Subcellular locations

Nucleus. Cytoplasm.

SPIB FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Sequence specific transcriptional activator which binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. Promotes development of plasmacytoid dendritic cells (pDCs), also known as type 2 DC precursors (pre-DC2) or natural interferon (IFN)-producing cells. These cells have the capacity to produce large amounts of interferon and block viral replication. May be required for B-cell receptor (BCR) signaling, which is necessary for normal B-cell development and antigenic stimulation.

SPIB Sequence

DDBJ

EMBL

GenBank

SPIB 3D structure

ModBase

SPIB interaction

STRING

SPIB Proteomic

PRIDE

SPIB Genome annotation

Ensembl

GeneID

KEGG

UCSC

SPIB Organism specific

CTD

MGI

SPIB Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

SPIB Gene expression

Bgee

ArrayExpress

Genevestigator

SPIB Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY