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Human Proliferating cell nuclear antigen (aa 1-261 )

PCNA Swiss Prot#

P12004

PCNA Protein names

Proliferating cell nuclear antigen (PCNA) (Cyclin)

PCNA Gene names

PCNA

Organism

Homo sapiens (Human)

PCNA Entry name

PCNA_HUMAN

PCNA Codon optimized cDNA(gene) Clone

PCNA Cat #

RPY0414

Tag

PCNA contains A 6x histidine tag

PCNA Formulation

Liquid

PCNA Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

PCNA Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant PCNA Protein

PCNA Cat #

PY0414

PCNA Source

recombinant

PCNA Applications

Western Blot, SDS-Page or may be used for other applications determined by user

PCNA Purity

>90%, as determined by SDS-PAGE under reducing conditions

PCNA Activity

N/A

Tag

PCNA Contains A 6x histidine tag

PCNA Formulation

Liquid

PCNA Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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PCNA family

PCNA family

PCNA Subcellular locations

Nucleus.

PCNA FUNCTION According to UniProtKB Swiss Prot

FUNCTION: This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand. Induces a robust stimulatory effect on the 3'-5' exonuclease and 3'-phosphodiesterase, but not apurinic-apyrimidinic (AP) endonuclease, APEX2 activities. Has to be loaded onto DNA in order to be able to stimulate APEX2.

PCNA Sequence

DDBJ

EMBL

GenBank

PCNA 3D structure

ModBase

PCNA interaction

STRING

PCNA Proteomic

PRIDE

PCNA Genome annotation

Ensembl

GeneID

KEGG

UCSC

PCNA Organism specific

CTD

MGI

PCNA Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

PCNA Gene expression

Bgee

ArrayExpress

Genevestigator

PCNA Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY