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Mouse RBPJ-interacting tubulin-associated protein (aa 1-253 )

Rita Swiss Prot#

Q9D1H0

Rita Protein names

RBPJ-interacting and tubulin-associated protein

Rita Gene names

Rita

Organism

Mus musculus (Mouse)

Rita Entry name

RITA_MOUSE

Rita Codon optimized cDNA(gene) Clone

Rita Cat #

RPY0399

Tag

Rita contains A 6x histidine tag

Rita Formulation

Liquid

Rita Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Rita Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Rita Protein

Rita Cat #

PY0399

Rita Source

recombinant

Rita Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Rita Purity

>90%, as determined by SDS-PAGE under reducing conditions

Rita Activity

N/A

Tag

Rita Contains A 6x histidine tag

Rita Formulation

Liquid

Rita Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Rita family

RITA family

Rita Subcellular locations

Cytoplasm. Nucleus. Cytoplasm > cytoskeleton > centrosome.

Rita FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Tubulin-binding protein that acts as a negative regulator of Notch signaling pathway. Shuttles between the cytoplasm and the nucleus and mediates the nuclear export of RBPJ/RBPSUH, thereby preventing the interaction between RBPJ/RBPSUH and NICD product of Notch proteins (Notch intracellular domain), leading to down-regulate Notch-mediated transcription. May play a role in neurogenesis (By similarity).

Rita Sequence

DDBJ

EMBL

GenBank

Rita 3D structure

ModBase

Rita interaction

STRING

Rita Proteomic

PRIDE

Rita Genome annotation

Ensembl

GeneID

KEGG

UCSC

Rita Organism specific

CTD

MGI

Rita Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Rita Gene expression

Bgee

ArrayExpress

Genevestigator

Rita Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY