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Rat Rho-related GTP-binding protein RhoB (aa 1-196 )

Arhb Swiss Prot#

P62747

Arhb Protein names

Rho-related GTP-binding protein RhoB

Arhb Gene names

Rhob Arhb

Organism

Rattus norvegicus (Rat)

Arhb Entry name

RHOB_RAT

Arhb Codon optimized cDNA(gene) Clone

Arhb Cat #

RPY0274

Tag

Arhb contains A 6x histidine tag

Arhb Formulation

Liquid

Arhb Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Arhb Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Arhb Protein

Arhb Cat #

PY0274

Arhb Source

recombinant

Arhb Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Arhb Purity

>90%, as determined by SDS-PAGE under reducing conditions

Arhb Activity

N/A

Tag

Arhb Contains A 6x histidine tag

Arhb Formulation

Liquid

Arhb Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Arhb family

Small GTPase superfamily, Rho family

Arhb Subcellular locations

Late endosome membrane; Lipid-anchor. Cell membrane; Lipid-anchor. Nucleus.

Arhb FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Mediates apoptosis in neoplastically transformed cells after DNA damage. Not essential for development but affects cell adhesion and growth factor signaling in transformed cells. Plays a negative role in tumorigenesis as deletion causes tumor formation. Involved in intracellular protein trafficking of a number of proteins. Targets PKN1 to endosomes and is involved in trafficking of the EGF receptor from late endosomes to lysosomes. Also required for stability and nuclear trafficking of AKT1/AKT which promotes endothelial cell survival during vascular development (By similarity).

Arhb Sequence

DDBJ

EMBL

GenBank

Arhb 3D structure

ModBase

Arhb interaction

STRING

Arhb Proteomic

PRIDE

Arhb Genome annotation

Ensembl

GeneID

KEGG

UCSC

Arhb Organism specific

CTD

MGI

Arhb Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Arhb Gene expression

Bgee

ArrayExpress

Genevestigator

Arhb Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY