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Rat ADP-ribosylation factor-like protein 2 (aa 1-184 )

Arl184 Swiss Prot#

O08697

Arl184 Protein names

ADP-ribosylation factor-like protein 2

Arl184 Gene names

Arl2 Arl184

Organism

Rattus norvegicus (Rat)

Arl184 Entry name

ARL2_RAT

Arl184 Codon optimized cDNA(gene) Clone

Arl184 Cat #

RPY0229

Tag

Arl184 contains A 6x histidine tag

Arl184 Formulation

Liquid

Arl184 Storage

Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

Arl184 Applications

Applications: 1. Codon-optimized cDNA(gene) sequence designed for protein production in both E.coli and Mammalian cell. The cDNA(gene) has been cloned into E.coli expression vector with 6x Histidine tag.2. May be used as RNAi assistance to restore the loss-of-function.

Recombinant Arl184 Protein

Arl184 Cat #

PY0229

Arl184 Source

recombinant

Arl184 Applications

Western Blot, SDS-Page or may be used for other applications determined by user

Arl184 Purity

>90%, as determined by SDS-PAGE under reducing conditions

Arl184 Activity

N/A

Tag

Arl184 Contains A 6x histidine tag

Arl184 Formulation

Liquid

Arl184 Storage

;. Storage at -20℃ to −80℃ Upon receipt. Avoid repeated freeze-thaw cycles.

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Arl184 family

Small GTPase superfamily, Arf family

Arl184 Subcellular locations

Mitochondrion intermembrane space. Cytoplasm > cytoskeleton > centrosome. Nucleus. Cytoplasm.

Arl184 FUNCTION According to UniProtKB Swiss Prot

FUNCTION: Small GTP-binding protein which cycles between an inactive GDP-bound and an active GTP-bound form, and the rate of cycling is regulated by guanine nucleotide exchange factors (GEF) and GTPase-activating proteins (GAP). GTP-binding protein that does not act as an allosteric activator of the cholera toxin catalytic subunit. Regulates formation of new microtubules and centrosome integrity. Prevents the TBCD-induced microtubule destruction. Participates in association with TBCD, in the disassembly of the apical junction complexes. Antagonizes the effect of TBCD on epithelial cell detachment and tight and adherens junctions disassembly. Together with ARL2, plays a role in the nuclear translocation, retention and transcriptional activity of STAT3. Component of a regulated secretory pathway involved in Ca(2+)-dependent release of acetylcholine. Required for normal progress through the cell cycle (By similarity).

Arl184 Sequence

DDBJ

EMBL

GenBank

Arl184 3D structure

ModBase

Arl184 interaction

STRING

Arl184 Proteomic

PRIDE

Arl184 Genome annotation

Ensembl

GeneID

KEGG

UCSC

Arl184 Organism specific

CTD

MGI

Arl184 Phylogenomics

eggNOG

GeneTree

HOGENOM

HOVERGEN

InParanoid

OrthoDB

PhylomeDB

OMA

Arl184 Gene expression

Bgee

ArrayExpress

Genevestigator

Arl184 Family and domain

InterPro

PROSITE

ProtoNet

FOR in vitro RESEARCH USE ONLY